Wednesday, February 26, 2025

Basic terms commonly used in microbiology:

General Microbiology Terms

  • Microorganism (Microbe) – A microscopic organism, such as bacteria, fungi, viruses, and protozoa.
  • Pathogen – A microorganism that causes disease.
  • Host – An organism that harbors a microbe or pathogen.
  • Infection – The invasion and multiplication of microorganisms in a host.
  • Contamination – The presence of unwanted microorganisms.
  • Sterilization – The process of killing or removing all microorganisms, including spores.
  • Disinfection – The process of killing or inhibiting pathogens on inanimate objects.
  • Antiseptic – A substance that inhibits microbial growth on living tissue.

Bacteria-Related Terms

  • Prokaryote – A unicellular organism without a nucleus (e.g., bacteria).
  • Gram Staining – A technique to classify bacteria as Gram-positive (purple) or Gram-negative (pink) based on cell wall structure.
  • Aerobic – Microorganisms that require oxygen to grow.
  • Anaerobic – Microorganisms that grow in the absence of oxygen.
  • Facultative Anaerobe – Bacteria that can grow with or without oxygen.
  • Obligate Anaerobe – Bacteria that cannot survive in the presence of oxygen.
  • Endospore – A resistant, dormant structure formed by some bacteria (e.g., Bacillus, Clostridium).

Fungi & Viruses

  • Fungi – Eukaryotic microorganisms, including molds and yeasts.
  • Hyphae – Thread-like structures in fungi.
  • Mycelium – A network of hyphae.
  • Dimorphic Fungi – Fungi that exist as both yeast and mold forms.
  • Virus – A non-living infectious agent consisting of genetic material (DNA or RNA) enclosed in a protein coat.
  • Capsid – The protein coat of a virus.
  • Envelope – A lipid membrane surrounding some viruses.
  • Bacteriophage – A virus that infects bacteria.

Microbial Growth & Control

  • Culture – The growth of microorganisms in a nutrient medium.
  • Colony – A visible mass of microbial cells arising from a single cell.
  • Agar – A solidifying agent used in culture media.
  • Incubation – The process of maintaining optimal growth conditions for microorganisms.
  • Lag Phase – The initial phase of bacterial growth where cells adjust to the environment.
  • Log Phase – The phase of exponential bacterial growth.
  • Stationary Phase – Growth rate slows as nutrients deplete.
  • Death Phase – The phase where bacterial cells die due to lack of nutrients.

Immunology & Pathogenicity

  • Antigen – A substance that triggers an immune response.
  • Antibody – A protein produced by the immune system that recognizes and binds to antigens.
  • Virulence – The degree of pathogenicity of a microorganism.
  • Toxin – A harmful substance produced by bacteria (e.g., exotoxin, endotoxin).
  • Vaccine – A preparation that stimulates immunity against a specific pathogen.


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